Image source: Why does Japan care so much about Blood Types?
ABO type, these are called antigens and are found in distribution throughout the human body. Most people are aware that Type O is a blood group that has a lot of protection by virtue of the fact that it carries antibodies to both blood group A and blood group B. If you're blood Type is O you cannot receive blood from a person who the type A or type B, you can only receive from another O.
Antigen: molecules that stimulate a response by T and B cells, surface proteins found on cells or viruses or environmental molecules
( like pollen or asbestos).
Antibodies are proteins found in blood or other bodily fluids of vertebrates, identify and destroy foreign objects such as bacteria and viruses, are proteins that recognize a specific antigen, bind to foreign antigens, which attract macrophages. Abbreviation for antibodies: Ig
Blood Group A
- Arose at the dawn of agriculture (1, 2)
- type A+ - has A and Rh antigens
A- blood - has only A antigens
Blood Group B
- Developed between 10,000 and 15,000 years ago in the Himalayan highlands (1)
- B+ blood - has B and Rh antigens
B- blood - produces anti-A, anti-Rh
Blood Group AB
- Is a modern blending of A and B (1)
- AB+ blood - produces no antibodies
AB- blood - has only A and B antigens
Blood Group O
- Arose in our hunter-gatherer ancestors in Africa (1)
- O+ blood - has only Rh antigens
O- blood - produces anti-A, anti-B, and anti-Rh
History of Blood Typing
In 1900 the Austrian physician Karl Landsteiner first discovered blood types, winning the Nobel Prize in Physiology or Medicine for his research in 1930.
Jul 15, 2014. Future - Why do we have blood types? - BBC
1921: Table 1: BLOOD GROUPS AND SUSCEPTIBILITY TO DISEASE: A REVIEW
BY J. A. FRASER ROBERTS Clinical Genetics Research Unit, Institute of Child Health, The Hospital for Sick Children, Great Ormond Street, London.
Brit. J. prev. soc. Med. (1957), 11, 107-125. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1058666/pdf/brjprevsmed00047-0001.pdf
Buchanan and Higley analyzed the results for 2,446 patients grouped at the Mayo Clinic from BLOOD GROUPS AND SUSCEPTIBILITY TO DISEASE January 1917 to May 1921. They classified the patients into seventeen diseases or groups of diseases, with a residual miscellaneous group.
A summary of the figures is presented in Table 1.
Having a specific Blood Type does not result in the disease it merely suggest that one is prone to develop the condition if possible risk factors are not avoided (smoking, environmental toxin overload, high ongoing stress, malnutrition, etc ...). Understanding the potential to develop a disease goes a long way in preventing the disease for ever developing. See more disease linked to blood type.
Henoch-Schonlein purpura (also known as IgA vasculitis) is a disorder that causes the small blood vessels in your skin, joints, intestines, and kidneys to become inflamed and bleed.(2) Immunoglobulin A (IgA) vasculitis (Henoch-Schonlein purpura (HSP)) is the most common vasculitis in children. It is characterized by purpuric rash, arthritis, gastrointestinal, and/or renal involvement.(3)
Characteristics of Henoch-Schonlein purpura include:
- Rash (purpura). Reddish-purple spots that look like bruises develop on the buttocks, legs and feet. The rash can also appear on the arms, face and trunk and may be worse in areas of pressure, such as the sock line and waistline.
- Swollen, sore joints (arthritis). People with Henoch-Schonlein purpura often have pain and swelling around the joints — mainly in the knees and ankles. Joint pain sometimes precedes the classical rash by one or two weeks. These symptoms subside when the disease clears and leave no lasting damage.
- Digestive tract symptoms. Many children with Henoch-Schonlein purpura develop belly pain, nausea, vomiting and bloody stools. These symptoms sometimes occur before the rash appears.
- Kidney involvement. Henoch-Schonlein purpura can also affect the kidneys. In most cases, this shows up as protein or blood in the urine, which you may not even know is there unless you have a urine test done. Usually this goes away once the illness passes, but some people develop persistent kidney disease.
2. IgA vasculitis (Henoch–Shönlein purpura) in adults: Diagnostic and therapeutic aspects
Alexandra Audemard-Verger, et al., Autoimmunity Reviews. Volume 14, Issue 7, July 2015, Pages 579-585
3. Indications and efficiency of dapsone in IgA vasculitis (Henoch-Schonlein purpura): case series and a review of the literature
Céline Roman,et al., European Journal of Pediatrics volume 178, pages1275–1281(2019)
3. Above Image. Unilateral lower leg purpura. Satoshi Ogawa, Masahiro Oka, Makoto Kunisada, Chikako Nishigori. Dermatology Online Journal 19 (1): 16